It has been achieved by Spanish researchers from the Higher Council for Scientific Research (CSIC), in collaboration with the Miguel Hernández University of Alicante and the emerging company (of the CSIC) Alodia Farmacéutica.
The two creams, which are already available in pharmacies, calm the skin hypersensitivity suffered by cancer patients, the CSIC reported in a note released today, in which it recalls that the use of chemotherapy agents for the treatment of different types of cancer It is associated with a high risk of neurological and motor complications, characterized by mechanical and cold hypersensitivity and numbness of the hands and feet.
“This is what is known as chemotherapy-induced peripheral neuropathy, which affects approximately a third of patients treated with standard doses of chemotherapy and almost all of those who receive high doses,” explained CSIC researcher Rosario González- Muñiz, from the Institute of Medicinal Chemistry (IQM-CSIC).
The scientist has specified that in these patients, the functionality of the peripheral nervous system is impaired and, when this peripheral neuropathy affects the patient’s quality of life, chemotherapy treatment is usually reduced or even suspended.
In recent years, the team led by this CSIC researcher, in collaboration with Antonio Ferrer’s group at the Miguel Hernández University (UHM) in Elche, has worked in this field, and thanks to funding from the Community of Madrid and the collaboration with the pharmaceutical company Alodia Farmacéutica has already begun the pharmaceutical development of these molecules for the topical treatment of peripheral neuropathy.
This company first promoted the development of one of these molecules as a neurocosmetic ingredient, since safety tests indicated that the selected molecule in its pure form was neither irritant nor mutagenic, which allowed it to be registered as a cosmetic ingredient.
Later, two cosmetic preparations for hands and feet were formulated, especially sensitive when suffering from peripheral neuropathy, and these cosmetic formulations, after passing the studies of dermal absorption, thermal stability and effectiveness of the preservative to prevent bacterial contamination, began to be marketed in pharmacies .
The entrance Scientists achieve creams that relieve skin sensitivity due to chemotherapy was first published in diary TODAY.
